Synapse is an Infested rifle in Warframe that channels corrosive energy in a steady beam, letting you focus on one target and melt it over time.
It deals pure Corrosive damage, making it ideal for builds that exploit enemy armor and health types rather than relying solely on raw critical hits.
Unlike traditional rifles, Synapse is a held-fire weapon that scales damage the longer the beam stays on a target, combining very well with critical and elemental mods for consistent output.
How To Get Synapse?
Synapse blueprint can be researched in your Clan’s Bio Lab after completing prior Infested weapon research.
Once unlocked, the blueprint allows you to craft the rifle using resources from missions throughout the Origin System, such as Mutagen Mass, Circuits, and Nano Spores.
Since Synapse is untradeable, completing the Bio Lab research is the only guaranteed way to obtain it, making preparation and resource farming essential before starting construction.
Synapse Crafting Requirements
Synapse Blueprint
- 5 Mutagen Mass
- 30,000 Salvage
- 3,500 Circuits
- 2 Forma
- 30,000 Credits
Synapse Stats
Synapse fires a beam that ramps up damage over time while remaining on a single target, offering a different playstyle compared to standard hitscan rifles.
The following are Synapse’s stats:
PRIMARY | |
Fire Rate | 12 |
| Magazine | 70 |
Reload | 1.5 |
| Accuracy | Very High |
Trigger | HELD |
| Beam Range | 27 |
DAMAGE | |
Critical Chance | 39% |
| Critical Damage | 2.7x |
Status | 13% |
| Corrosive | 20 |
Synapse Tips
Hold the beam on high-priority targets to maximize damage ramping and take advantage of the weapon’s high critical chance.
Build for elemental damage in addition to Corrosive, as adding elements like Viral or Radiation increases effectiveness against specific enemy types.
Synapse performs best in single-target scenarios rather than crowd control, so focus on precision and controlled bursts to conserve ammo and maximize damage.
Its 0.5 ammo per tick cost means pairing it with mods that boost efficiency or critical damage can dramatically improve performance in longer fights.
Verdict
Synapse rewards careful aim and consistent fire, making it a weapon designed for players who prefer steady sustained damage over wide area attacks.
Its beam scales over time and benefits from both critical and elemental mods, giving it excellent performance against armored enemies and bosses.
While it isn’t suited for clearing crowds quickly, its precision, accuracy, and ramping damage make it a reliable choice for mid to late-game content when used strategically.
