Nidus can be considered to be the harbinger of infestation, spreading corruption across the battlefield with rupturing strikes, grasping tendrils, and a constant swarm of mutated energy.
With enough Mutation Stacks, he becomes a powerhouse, dishing out massive damage while sustaining himself through healing and damage resistance.
His abilities offer a strong mix of offense, crowd control, and team support, making him a versatile and durable Warframe that can work alone or prove to be useful with others.
Nidus Builds
1) Standard Build (All Around Build)
The Standard Build we have for Nidus is meant to provide him with the means to cast his abilities with enhanced stats on them, mostly in Ability Strength and Ability Range.
With a higher amount of Ability Strength, Virulence, and Ravenous should be able to deal more damage, while Parasitic Link will provide a better buff.
Since Nidus has no shields and needs energy at times, it is a great idea to use the Hunter Adrenaline or Rage mods to allow him to convert damage taken into energy.
This build provides enough range for Virulence to hit several enemies in a line while Larva can pull enemies from a good distance to gain Mutation Stacks.
2) Nuke Build (High Ability Strength Build)
Nidus is a powerful nuker, and some people don’t realize that yet until they understand that his Mutation Stacks make Virulence and Ravenous more effective.
With this Nuke Build, Nidus is capable of dealing very high amounts of damage with Virulence and Ravenous, provided that he can get stacks.
All you need to do is pull enemies in with Larva and use Virulence to deal damage and get stacks while casting Ravenous now and then.
The high damage from Virulence is more than enough to kill higher-level enemies, and Ravenous can add to that as well as improve survivability with high health regeneration.
3) Abundant Mutation Build (Max Mutation Stacks Build)
The Abundant Mutation Build is quite similar to the Nuke Build, but with a smaller amount of Ability Strength sacrificed for an additional max 200 Mutation Stacks.
With even more Mutation Stacks, Nidus will be able to deal a lot of damage with Virulence and Ravenous, since they are affected by the stacks.
Virulence will gain more damage when hitting enemies, while the maggots that explode from Ravenous will now deal more damage.
This build focuses on gaining as many stacks as possible to, later on, deal more damage as missions become prolonged.
4) Teeming Virulence Build (High Critical Chance Build)
A more different build and one that is less focused on abilities, the Teeming Virulence Build focuses on providing Nidus with an insane amount of Critical Chance.
Teeming Virulence will provide Nidus with a buff in Critical Chance whenever he hits 4 or more enemies with the Virulence ability.
With this build, the Critical Chance provided by the buff reaches up to 405% and lasts 22.73 seconds before it disappears.
It is not difficult to hit 4 enemies with Virulence, and since this is so easy to do, you can expect to be running and gunning with that 405% Critical Chance majority of the time.
5) Larva Burst Build (High Range Exploding Build)
Our Larva Burst Build makes use of the Larva Burst augments, which allow you to detonate the pod that is released when you reactivate the ability.
The technique with this build is simply to pull enemies with Larva and then to reactivate the ability to detonate them, dealing more damage per enemy grabbed.
With a pull distance of 31.8 meters from this build and 537 Toxin Damage per enemy, Larva Build should be able to grab several enemies and detonate the pod for excessive damage.
The damage stacks for every enemy that is grabbed while the explosion will be a radius around the pod, and with a high Ability Range, you can grab enemies from further distances.
6) Insatiable Build (Fast Mutation Stacks Build)
You can never have too many Mutation Stacks, and if you love to collect them with Nidus, the Insatiable Build is perfect for you.
Combining the Abundant Mutations and Insatiable mod, this build aims to quickly maximize the number of Mutation Stacks you have.
Insatiable provides you with a chance to get an extra Mutation Stack whenever you obtain one while standing in an area where Ravenous is cast.
This allows you to quickly increase your Mutation Stacks early on in a mission for dealing out more damage with Virulence and the maggots from Ravenous.
Also click the below link to know “How to Get Nidus & Nidus Prime” in the game:
Verdict
Nidus has a decent amount of Health and Armor even at a lower rank, but as this increases, he becomes even more durable.
During the start of a mission, ensuring that you utilize Virulence to build up mutations is important, as this is needed for some of his abilities that later rely on your mods to have better effects.
Making your build focus on more than one ability may sometimes be crucial, as Nidus’ abilities often go hand in hand, and having a decent balance makes him all the more effective against enemies.







Hi, I was looking at the Oberon strength build and I was wondering is there a certain ability rotation to get the most out of that build. I am pretty new to the game.
“A good order to use your abilities in would be to start off with Reckoning so you knock enemies down which will give you a good amount of time to cast Hallowed Ground and from there on you can continue by dishing out more damage by casting Smite repeatedly along with Reckoning every once in a while to avoid them from retaliating. Smite can also be used to knock them down from afar so you have time to move up to them to use Reckoning.
Using a melee weapon in between casting your abilities can also deal a good amount of damage, conserving energy and taking advantage of the enemies being knocked down or affected by the radiation status effect (causes them to attack each other) from Hallowed Ground.”