Farming the right Lair Boss can save you a massive amount of time when trying to target specific Uniques for your build, and other random ones that drop may surprise you.
Season 13 expands the Lair Boss system even further, adding new Warlock Uniques, updated loot pools, and a revised hoard key structure across Sanctuary.
This guide covers every Lair Boss in Season 13, their locations, loot tables, hoard requirements, and the best bosses to farm for specific Unique items.
All Lair Bosses & Loot Tables in Season 13
Season 13 divides Lair Bosses into three tiers, with each one offering different rewards, difficulty levels, and Unique item pools. (These sections may be updated later)
Initiate Lair Bosses
Initiate Lair Bosses are the first tier of endgame bosses and are commonly farmed for Uniques, Mythic Uniques, and Greater Lair Keys.
Lord Zir (Ancient’s Seat – Fractured Peaks)
- Hands of the Worldbreaker (Warlock)
- X’Fal’s Corroded Signet (All Classes)
- Twin Strikes (Barbarian)
- Fields of Crimson (Barbarian)
- The Umbracrux (Rogue)
- Skyhunter (Rogue)
- Kilt of Blackwing (Druid)
- Dirge of Odium (Warlock)
- Fleshwrit Carapace (Warlock)
- Dirge of Odium (Warlock)
Varshan (Malignant Burrow – Hawezar)
- Shard of Verathiel (All Classes)
- Razorplate (All Classes)
- Overkill (Barbarian)
- Greatstaff of the Crone (Druid)
- The Hand of Naz (Necromancer)
- Thrice-Woven Nightmare (Warlock)
- Ae’grom’s Schism (Warlock)
- Seal of the Ophanim (Warlock)
- Bindings of Attrition (Warlock)
- Godslayer Crown (All Classes)
- Eye of Baal (Warlock)
Grigoire (Hall of the Penitent – Dry Steppes)
- Paingorger’s Gauntlets (All Classes)
- Godslayer Crown (All Classes)
- Azurewrath (Barbarian)
- The Mortacrux (Necromancer)
- Cage of Madness (Warlock)
- Sire of Sin (Warlock)
- Hands of the Worldbreaker (Warlock)
- Seed of Horazon (Warlock)
- The Beast in the Ice (Glacial Fissure – Fractured Peaks)
- Signet of Pelghain (All Classes)
- Endurant Faith (All Classes)
- Howl from Below (Necromancer)
- Deathless Visage (Necromancer)
- The Eightfold Idol (Warlock)
- Kabraxis’ Will (Warlock)
- Hellhound’s Sabatons (Warlock)
- Ae’grom’s Schism (Warlock)
- Soulbrand (All Classes)
Urivar (Fields of Judgement – Nahantu)
- Yen’s Blessing (All Classes)
- Temerity (All Classes)
- Gospel of the Devotee (Necromancer)
- Infernal Homunculus (Warlock)
- The Blade of Sight Aflame (Warlock)
- Cowl of Malefic Torment (Warlock)
Greater Lair Bosses
Greater Lair Bosses are tougher encounters that require Greater Lair Keys and provide stronger endgame farming opportunities for Mythic Uniques.
Duriel (Gaping Crevasse – Kehjistan)
- Crown of Lucion (All Classes)
- Razorplate (All Classes)
- Mutilator Plate (Necromancer)
- Scourge of Duriel (Warlock)
- Rictus of Terror (Warlock)
- Morlu Fleshward (Warlock)
- Gauntlets of Sheol (Warlock)
Andariel (Hanged Man’s Hall – Kehjistan)
- Endurant Faith (All Classes)
- Godslayer Crown (All Classes)
- Kessime’s Legacy (Necromancer)
- Night Terror (Warlock)
- Gauntlets of Sheol (Warlock)
- Scepter of the Three (Warlock)
- Dirge of Odium (Warlock)
- Anathema of the Primes (Warlock)
Harbinger of Hatred (Harbinger’s Den – Nahantu)
- Tyrael’s Might (All Classes)
- Temerity (All Classes)
- Scourge of Duriel (Warlock)
- The Fecund Seal (Warlock)
- Spine of Tathamet (Warlock)
- Hellhound’s Sabatons (Warlock)
The Butcher (The Broiler – Kehjistan)
- Soulbrand (All Classes)
- Godslayer Crown (All Classes)
- The Butcher’s Cleaver (All Classes)
- Razorplate (All Classes)
- Moloch’s Beating Flame (Warlock)
- Hellbrand Signet (Warlock)
- Lurid Pact (Warlock)
- Eye of Baal (Warlock)
Exalted Lair Bosses
Exalted Lair Bosses are pinnacle endgame encounters with some of the best rewards and highest Mythic Unique drop potential in Season 13.
Belial (Palace of the Deceiver – Kehjistan)
- Rewards can include loot from other Lair Boss pools
- Guaranteed Ancestral Unique
- Increased Mythic Unique drop chance
Astaroth (Escalating Nightmare – Randomized)
- Crown of Lucion (All Classes)
- Ring of the Sacrilegious Soul (Necromancer)
- Footfalls of the Waning World (Warlock)
- Hecaton Chasm (Warlock)
- Bindings of Attrition (Warlock)
- Litany of Sable (Warlock)
Bartuc (Infernal Hordes – 666 Aether Requirement)
- Crown of Lucion (All Classes)
- Soulbrand (All Classes)
- The Hemat Stone (Warlock)
- Sashes of the Wretched (Warlock)
- Eye of Baal (Warlock)
How To Open Lair Boss Hoards?
Lair Bosses no longer require summoning materials before the fight, as the system now focuses on opening reward hoards after defeating them.
Initiate Lair Bosses require a standard Lair Key, while Greater Lair Bosses require Greater Lair Keys to unlock their hoards afterward.
Belial uses Betrayer’s Husks instead, while Astaroth and Bartuc are tied to Escalating Nightmares and Infernal Horde progression systems.
New Lair Key System in Season 13
Season 13 replaced the older boss-specific summoning materials with a simpler key system tied directly to opening Lair Boss hoards.
Instead of farming separate materials for every boss summon, Initiate Lair Bosses now use a general Lair Key to unlock their hoards after the fight.
Greater Lair Bosses require Greater Lair Keys instead, giving access to better rewards and improved Mythic Unique farming opportunities.
Exalted Lair Bosses work differently, as Belial requires Betrayer’s Husks while Astaroth and Bartuc are tied to Escalating Nightmares and Infernal Horde activities.
Best Lair Bosses To Farm
Andariel is currently one of the best bosses for farming Warlock Uniques due to the number of powerful Season 13 items in her loot pool.
Bartuc is another excellent option for Demonology-focused builds because several summon-related Warlock Uniques can drop from his hoard.
Belial remains one of the most rewarding bosses overall since his hoard can pull rewards from multiple Lair Boss pools at once.
Verdict
Season 13 gives players much more control over Unique farming thanks to the updated Lair Boss hoard and key systems.
Knowing which boss drops the item you need can greatly speed up progression and reduce wasted farming time during endgame content.
Whether you are farming Mythic Uniques, Warlock gear, or build-defining items, learning the Season 13 Lair Boss loot tables is extremely important for efficient farming.
